منابع مشابه
Vitamin A compounds and analogs as inhibitors of mixed-function oxidases that metabolize carcinogenic polycyclic hydrocarbons and other compounds.
Fourteen vitamin A compounds and analogs have been evaluated as inhibitors of microsomal mixed-function oxi dases from liver and lung tissues of mice and hamsters. With liver microsomes, benzo(a)pyrene (BP) is metabolized, by one pathway, to a product (BP-X) which is tightly bound to reaction components. The Km for BP in this reaction is 10 ± 2 /xM.The formation of BP-X is strongly inhibited b...
متن کاملThe carcinogenic activity of some new derivatives of aromatic hydrocarbons; compounds related to 1,2-benzanthracene.
In 1939 a program of investigation was undertaken in collaboration with Professor Louis F. Fieser and his associates at Harvard University, directed toward a further study of the chemistry of artificial carcinogenesis. The main task was a biological testing for carcinogenicity of a number of new hydrocarbon derivatives synthesized by Dr. Fieser's group. Although the chief purpose of this paper ...
متن کاملDegradation of Hydrocarbons and Lignin-like compounds by Alcaligenes sp. strain 3k isolated from Ilorin
The primary goal of this study was to isolate hydrocarbon-degrading organisms and assess their ability to bioremediate petroleum-contaminated soil and water. Nigeria is one of the major oil producing countries and petroleum contamination is widespread in agricultural soil. Alcaligenes sp. strain 3k was isolated from a kerosene-polluted soil in Ilorin, Nigeria. We also assessed its ability to de...
متن کاملDegradation of Hydrocarbons and Lignin-like compounds by Alcaligenes sp. strain 3k isolated from Ilorin
The primary goal of this study was to isolate hydrocarbon-degrading organisms and assess their ability to bioremediate petroleum-contaminated soil and water. Nigeria is one of the major oil producing countries and petroleum contamination is widespread in agricultural soil. Alcaligenes sp. strain 3k was isolated from a kerosene-polluted soil in Ilorin, Nigeria. We also assessed its ability to de...
متن کاملInteraction of carcinogenic hydrocarbons with tissues. VIII. Binding of tritiumlabeled hydrocarbons to the soluble proteins of mouse skin.
Studies were carried out in which the binding of thirteen carcinogenic and noncarcinogenic hydrocarbons to the soluble proteins of mouse skin was compared. A good quantitative correlation was found to exist between the binding of the hydrocarbons to a particular protein fraction (protein fraction 1) obtained from mouse skin, which migrates toward the cathode with a relative mobility of +0.23, i...
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ژورنال
عنوان ژورنال: The American Journal of Cancer
سال: 1937
ISSN: 0099-7374
DOI: 10.1158/ajc.1937.555